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New, more expensive migraine drugs are no more effective against the throbbing headaches than traditional painkillers, and even performed worse than an older range of treatments called triptans, said a massive global analysis Thursday.

Rap mogul Sean "Diddy" Combs will remain imprisoned pending trial on racketeering and sex trafficking charges, after a judge denied his appeal Wednesday.

The Milwaukee Brewers became the first Major League Baseball team to clinch a division title on Wednesday, locking up the National League Central for the third time in four years.

Inter Milan boss Simone Inzaghi said the Italian champions produced a "giant performance" to leave Manchester City frustrated in a 0-0 draw to begin their Champions League campaign on Wednesday.

Wall Street stocks dipped Wednesday after the Federal Reserve announced a half a percentage-point interest rate cut and its chair promised a "careful" approach to lowering rates following progress in countering US inflation.

Manchester City made a sluggish start to their Champions League campaign as they drew 0-0 against Inter Milan on Wednesday, while Paris Saint-Germain needed a last-minute goal to beat tournament newcomers Girona.

Veteran Beauden Barrett was recalled to the New Zealand team named Thursday to face Australia in The Rugby Championship as All Blacks head coach Scott Robertson made four changes.

A second wave of device explosions killed 20 people and wounded more than 450 others on Wednesday in Hezbollah strongholds in Lebanon, officials said, stoking fears of an all-out war with Israel.

Tottenham needed two late goals from Djed Spence and Brennan Johnson to beat second-tier Coventry 2-1 and avoid a shock League Cup exit on Wednesday.

Paris Saint-Germain were grateful to a last-minute howler from goalkeeper Paulo Gazzaniga as they snatched a 1-0 win over European debutants Girona in their opening game of the new-look Champions League on Wednesday.

English winger Jamie Gittens scored twice in the final 15 minutes to seal Borussia Dortmund a 3-0 win at Club Brugge in their Champions League opener on Wednesday.

Manchester City's quest to reconquer the Champions League began with a whimper on Wednesday as Inter Milan held out for a 0-0 draw at the Etihad.

French Olympic swimming hero Leon Marchand said Wednesday his record-breaking exploits in the Paris pool have changed his life so much that he often needs to don a disguise to evade attention.

YouTuber MrBeast has been named in a lawsuit claiming participants in his $5 million jackpot game show were exploited.

Coco Gauff, last year's US Open champion, and coach Brad Gilbert announced on Wednesday they have split after 14 months together.

Senior United Nations officials warned on Wednesday that hundreds of thousands of lives are at risk in the besieged Sudanese town of El-Fasher, amid signs that the fighting could soon escalate.

Disgraced US movie producer Harvey Weinstein pleaded not guilty on Wednesday to a new sex crime charge in New York.

Venezuela's opposition candidate Edmundo Gonzalez Urrutia said Wednesday he had been coerced into signing a letter distributed by Venezuelan authorities in which he supposedly conceded election defeat to strongman President Nicolas Maduro.

Russia's counteroffensive to retake Ukrainian-held territory in the Kursk region has been "stopped", a spokesman from Ukraine's military administration there told AFP on Wednesday, after Moscow said it was beginning to repel the surprise incursion.

Elon Musk's X social network carried out an automatic update overnight on phone applications that allowed it to bypass a ban in Brazil, an association of internet providers said Wednesday.

A second wave of device explosions killed 14 people and wounded more than 450 others on Wednesday in Hezbollah strongholds in Lebanon, officials said, stoking fears of an all-out war with Israel.

The US Federal Reserve cut its key lending rate by half a percentage-point Wednesday in its first reduction since the Covid-19 pandemic, sharply lowering borrowing costs just before November's presidential election.

Arsenal captain Martin Odegaard will be out "for a while" with an ankle injury he suffered on international duty with Norway, manager Mikel Arteta said on Wednesday.

India's plans to expand coal mining could double emissions of the potent greenhouse gas methane from its domestic coal sector by 2029, threatening its climate goals, a report warned Thursday.

China presents the top challenge to the United States in its history, surpassing the Cold War, a top US official said Wednesday, as he urged Europe to get tougher on Beijing.

The US Federal Reserve cut its key lending rate by half a percentage-point Wednesday in its first reduction since the onset of the Covid-19 pandemic, sharply lowering borrowing costs shortly before November's presidential election.

Saudi club Al Nassr announced Wednesday the appointment of Stefano Pioli as coach of the side headed up by Portugal star Cristiano Ronaldo.

British boat Ineos Britannia booked its place in the final of the Louis Vuitton Cup in Barcelona on Wednesday clinching the point it needed against Switzerland while American Magic fought back against the Italian Luna Rossa.

Roma sacked club icon Daniele De Rossi and replaced him with Ivan Juric on Wednesday after a poor start to the season which has left the Serie A team without a win and languishing near the relegation zone.

The Women's NBA, enjoying a record-shattering season of growth, announced Wednesday it will add an expansion club in Portland, Oregon, for the 2026 season.

Brazil's raging wildfires are being driven by people seeking to clear land for agriculture or arsonists out to sow havoc, a top police official told AFP, calling for harsher punishments for environmental crimes.

Boeing said Wednesday it would start temporary furloughs of professional and white-collar staff as it seeks to conserve cash amid a labor strike that has shuttered Seattle manufacturing plants.